Below you find the latest publications on PubMed that discuss the FinnDiane cohort. For a complete overview click here
- Apolipoprotein C-III predicts cardiovascular events and mortality in individuals with type 1 diabetes and albuminuriaCONCLUSIONS: The impact of apoC-III on MACE risk and mortality is restricted to those with albuminuria among individuals with type 1 diabetes. This study also revealed that apoC-III predicts DKD progression, independent of the initial DKD category.
- Glycemic control is not related to cerebral small vessel disease in neurologically asymptomatic individuals with type 1 diabetesCONCLUSIONS: We observed no association between glycemic control and cSVD in neurologically asymptomatic individuals with type 1 diabetes. This finding was unexpected considering the large number of signs of cerebrovascular pathology in these people after two decades of chronic hyperglycemia and warrants further studies searching for underlying factors of cSVD.
- Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetesCONCLUSIONS: Presence of cerebral small-vessel disease on brain MRI, particularly cerebral microbleeds, is associated with the severity of diabetic retinopathy.
- The impact of central obesity on the risk of hospitalization or death due to heart failure in type 1 diabetes: a 16-year cohort studyCONCLUSIONS: Central obesity associates with an increased risk of heart failure hospitalization or death in adults with type 1 diabetes, and WHtR may be a clinically useful screening tool.
- The Low-Expression Variant of <em>FABP4</em> Is Associated With Cardiovascular Disease in Type 1 DiabetesFatty acid binding protein 4 (FABP4) is implicated in the pathogenesis of cardiometabolic disorders. Pharmacological inhibition or genetic deletion of FABP4 improves cardiometabolic health and protects against atherosclerosis in preclinical models. As cardiovascular disease (CVD) is common in type 1 diabetes, we examined the role of FABP4 in the development of complications in type 1 […]