Below you find the latest publications on PubMed that discuss the FinnDiane cohort. For a complete overview click here
- CONCLUSIONS/INTERPRETATION: The current study detected 11 loci associated with DKD progression, identifying methylation changes predictive of early-stage DKD progression in type 1 diabetes for the first time. Future research is needed to establish prognostic DNA methylation markers for DKD progression.
- CONCLUSIONS: CMBs were related to a subtle, yet systematic impairment in cognition, whereas mild WMHs were not. The results provide insight into the development of early cSVD-related cognitive changes already in midlife and suggest an increased risk of cognitive decline in T1D.
- CONCLUSIONS: Elevated sRAGE is associated with increased odds of TRH in individuals with type 1 diabetes. sRAGE further stratifies high risk of incident CAD and ESKD, even after accounting for clinical variables. Along with eGFR, sRAGE may help to identify individuals at the highest risk of adverse cardiovascular and kidney outcomes.
- CONCLUSIONS: Healthcare professionals should assess presence of depression and monitor medication adherence at regular consultations, and whenever needed, should implement strategies to manage the depression in order to enhance adherence, which might ultimately lead to improved cardiovascular outcomes in type 1 diabetes.
- Characteristics of above 65-year-olds with type 1 diabetes in the Finnish diabetic nephropathy studyCONCLUSION: Above 65-year-olds were characterized by both factors generally related to positive and negative health outcomes. Additionally, different factors were found to be associated with reaching older age and with survival beyond the age of 65.
